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Tea consumption and risk of ovarian cancer.
Cancer Causes Control. 2010 May 20.
Nagle CM, et al
Genetics and Population Health, Queensland Institute of Medical Research, PO Royal Brisbane Hospital, Brisbane, QLD, 4029, Australia
Abstract
OBJECTIVE: Although the growth inhibitory effects of tea, particularly green tea, and tea polyphenols have been demonstrated in animal models of ovarian cancer, the results of epidemiological studies have been inconclusive.
METHODS:
We investigated this issue using data from an Australian population-based, case-control study (1,368 cases; 1,416 controls). We also systemically reviewed all the available evidence regarding the potential association between green tea and risk of ovarian cancer, given the abundance of bioavailable polyphenols and higher antioxidant capacity of green tea than black tea, to provide the best summary estimate of the association.
RESULTS: In our case-control study, while we found uniformly inverse odds ratios (OR) for tea drinkers compared to non-tea drinkers [4 + cups/day any tea OR 0.71 (95% CI 0.52-0.97); green tea OR 0.82 (95% CI 0.38-1.79); herbal tea OR 0.77 (95% CI 0.28-2.14): black tea OR 0.88 (95% CI 0.66-1.18)], we saw no dose-response trends.
Our meta-analysis provided some evidence that women who drink green tea have a lower risk of ovarian cancer, although the summary estimate did not reach statistical significance (0.58, 95% CI 0.33-1.01 for >/=1 cup/green tea day).
This result is consistent with two recent meta-analyses that evaluated the association of tea (all types combined) and ovarian cancer risk.
CONCLUSION: Overall, our findings provide some support for the hypothesis that tea consumption reduces the risk of ovarian cancer.
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In the Media on Tea!
Kombucha is steeped in controversy
The fermented tea drink looks like 'probiotic' health food to some, moldy risk to others
By Laura Vozzella
The Baltimore Sun
June 23, 2010
Herbal teas, including all the teas discussed in these pages, should not be consumed by persons who are pregnant or nursing, unless approved by your health care provider. Herbal teas may vary in their ingredients and some herbal tea components may interfere with other important medications. For example, there is some concern that green tea ingestion during pregnancy may reduce the absorption of folate, an important nutrient in fetal nervous system development.
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